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Royal Society of Chemistry, Chemical Communications, 4, p. 480-482, 2008

DOI: 10.1039/b716115h

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Site-specific N-terminal labelling of proteinsin vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry

This paper is available in a repository.
This paper is available in a repository.

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Abstract

N-Myristoyl transferase-mediated modification with azide-bearing substrates is introduced as a highly selective and practical method for in vitro and in vivo N-terminal labelling of a recombinant protein using bioorthogonal ligation chemistry.