Dissemin is shutting down on January 1st, 2025

Published in

Royal Society of Chemistry, Chemical Communications, 57(49), p. 6397, 2013

DOI: 10.1039/c3cc42981d

Links

Tools

Export citation

Search in Google Scholar

Mechanical unfolding of long human telomeric RNA (TERRA)

Journal article published in 2013 by Miguel Garavís, Rebeca Bocanegra, Elías Herrero-Galán, Carlos González ORCID, Alfredo Villasante, J. Ricardo Arias-Gonzalez, J. Ricardo Arias Gonzalez
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

We report the first single molecule investigation of TERRA molecules. By using optical-tweezers and other biophysical techniques, we have found that long RNA constructions of up to 25 GGGUUA repeats form higher order structures comprised of single parallel G-quadruplex blocks, which unfold at lower forces than their DNA counterparts.