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Royal Society of Chemistry, Organic and Biomolecular Chemistry, 22(8), p. 5133

DOI: 10.1039/c0ob00070a

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Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.

This paper is available in a repository.
This paper is available in a repository.

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Abstract

New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.