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Cambridge University Press, Epidemiology and Psychiatric Sciences, 02(23), p. 137-140

DOI: 10.1017/s2045796014000055

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Discordant twins as a tool to unravel the aetiology of bipolar disorder

Journal article published in 2014 by C. Fagnani, M. Bellani ORCID, J. C. Soares ORCID, M. A. Stazi, Soares Jc, Stazi Ma, P. Brambilla
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This paper is available in a repository.

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Abstract

This editorial focuses on discordant twins as a valuable epidemiological design for psychiatric aetiological research. First, we summarise the advantages and strengths of this design over the classical matched case-control study. Then, we draw attention to the use of this method in bipolar disorder, revising previous discordant-twin studies. A future greater use of discordant twins is desirable to gain further relevant insights in the aetiology of bipolar disorder.