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Royal Society of Chemistry, Soft Matter, 42(10), p. 8401-8405

DOI: 10.1039/c4sm01733a

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Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.