Published in
Royal Society of Chemistry, Biomaterials Science, 4(3), p. 581-585, 2015
DOI: 10.1039/c4bm00411f
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A novel hanging spherical drop system for the generation of cellular spheroids and high throughput combinatorial drug screening
Journal article published in 2015 by
Ana I. Neto 
,
Clara R. Correia,
M. I. Rial-Hermida,
Mariana B. Oliveira,
Isabel R. Hermida,
C. Alvarez-Lorenzo,
Carmen A. Lorenzo,
Rui L. Reis,
Joao F. Mano
,
Clara R. Correia,
M. I. Rial-Hermida,
Mariana B. Oliveira,
Isabel R. Hermida,
C. Alvarez-Lorenzo,
Carmen A. Lorenzo,
Rui L. Reis,
Joao F. Mano
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Abstract
A novel hanging spherical drop system based on the use of biomimetic superhydrophobic flat substrates allows one to generate arrays of independent spheroid bodies in a high throughput manner, in order to mimicin vivotumour models on the lab-on-chip scale.