Published in
Royal Society of Chemistry, Journal of Materials Chemistry, 40(22), p. 21382
DOI: 10.1039/c2jm34999j
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Polymer-gold nanohybrids with potential use in bimodal MRI/CT: Enhancing the relaxometric properties of Gd(III) complexes
Journal article published in 2012 by
Mariana Beija,
Yang Li,
Hien T. Duong 
,
Sophie Laurent,
Luce Vander Elst,
Robert N. Muller,
Andrew B. Lowe ,
Thomas P. Davis,
Cyrille Boyer
,
Sophie Laurent,
Luce Vander Elst,
Robert N. Muller,
Andrew B. Lowe ,
Thomas P. Davis,
Cyrille Boyer
This paper is available in a repository.
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Abstract
We present a new synthetic strategy to produce Gd(III)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12000 mM−1 s−1 per particle), indicative of highly efficient CT/MRI CAs.