Published in
Royal Society of Chemistry, Nanoscale, 1(6), p. 199-202, 2014
DOI: 10.1039/c3nr04730j
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Synthesis of Au–Fe3O4heterostructured nanoparticles for in vivo computed tomography and magnetic resonance dual model imaging
Journal article published in 2014 by
Jing Zhu,
Yinjie Lu,
Yonggang Li,
Jiang Jiang,
Liang Cheng,
Zhuang Liu 
,
Liang Guo,
Yue Pan,
Hongwei Gu
,
Liang Guo,
Yue Pan,
Hongwei Gu
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Abstract
Water-soluble Au-Fe3O4 heterostructured nanoparticles with high biocompatibility were synthesized and applied as a dual modality contrast agent. These nanoparticles present strong CT/MRI contrast enhancement in a rabbit model. Low concentrations of Au-Fe3O4 were found to obtain a similar effect to high concentrations of a commercial iodine agent in the CT image.