Published in
Royal Society of Chemistry, Molecular BioSystems, 5(2), p. 240
DOI: 10.1039/b518044a
Links
Tools
Covalent modification of a melanoma-derived antigenic peptide with a natural quinone methide. Preliminary chemical, molecular modelling and immunological evaluation studies.
Journal article published in 2006 by
Celine Douat-Casassus,
Nathalie Marchand Geneste,
Elisabeth Diez,
Céline Aznar,
Philippe Picard,
Serge Geoffre,
Aline Huet,
Marie-Lise Bourguet-Kondracki,
Nadine Gervois 
,
Francine Jotereau,
Stépyhane Quideau
,
Francine Jotereau,
Stépyhane Quideau
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
Published version:
archiving forbidden
Data provided by 
Abstract
A ligand Fit shap-directed docking methodology was used to identify the best position at which the melanoma-derived MHC class-I-HLA-A2-binding antigenic peptide ELAGIGILTV could be modified by attaching a small molecule capable of fitting at the interface of complementary determining regional (CDR) loops of a T-cell receptor (TCR)whilie triggering T-cell responses.