Published in
Royal Society of Chemistry, Chemical Communications, 29(49), p. 3046, 2013
DOI: 10.1039/c3cc39106j
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In vivo evidence of the targeting of cartilaginous tissue by pyridinium functionalized nanoparticles
Journal article published in 2013 by
Jessica Morlieras,
Jean-Michel Chezal,
Elisabeth Miot-Noirault,
Aurélien Vidal,
Sophie Besse,
David Kryza,
Charles Truillet,
Anna Mignot,
Rodolphe Antoine 
,
Philippe Dugourd,
Françoise Redini,
Lucie Sancey,
François Lux,
Pascal Perriat,
Marc Janier
and other authors.
,
Philippe Dugourd,
Françoise Redini,
Lucie Sancey,
François Lux,
Pascal Perriat,
Marc Janier
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Ultrasmall gadolinium based particles have been functionalized with positively charged pyridinium quaternary ammonium and labelled with 111In. Evidence of their active targeting properties towards proteoglycans has been demonstrated in vivo after intravenous injection into rats opening thus a route to cancer imaging and therapy.