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Royal Society of Chemistry, Journal of Materials Chemistry, 34(19), p. 6167

DOI: 10.1039/b905495b

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Antimicrobial activity of methylene blue and toluidine blue O covalently bound to a modified silicone polymer surface

Journal article published in 2009 by C. Piccirillo ORCID, S. Perni, J. Gil-Thomas, Polina Prokopovich, M. Wilson, J. Pratten, I. P. Parkin ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Methylene Blue or Toluidine Blue O were covalently bound to an activated silicone polymer by means of an amide condensation reaction. UV-visible absorption spectra confirmed that the dye was surface bound. The new polymers with covalently attached dye display significant bactericidal activity against Escherichia coli and Staphylococcus epidermidis with a 99.999% reduction in viable bacteria after four minutes exposure to a low power laser.