Encapsulated mitochondria to reprogram the metabolism of M2-type macrophages for anti-tumor therapy
Journal article published in 2024 by
Yonghui Wang,
Chang Liu,
Xiaodong Ma,
Anne Filppula,
Youbin Cui,
Jiangbin Ye,
Hongbo Zhang 
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Abstract
In this study, our innovative Mito@ZiF-8 system enhances the functionality of isolated mitochondria and reprograms M2 macrophage metabolism upon delivery, ultimately, reducing the tumorigenic potential of breast cancer cells.