Published in
Royal Society of Chemistry, Nanoscale, 2(3), p. 387-390
DOI: 10.1039/c0nr00436g
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Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles
Journal article published in 2011 by
Emanuela Occhipinti,
Paolo Verderio,
Antonino Natalello 
,
Elisabetta Galbiati,
Miriam Colombo,
Serena Mazzucchelli,
Agnese Salvadè,
Paolo Tortora,
Sm Doglia,
Davide Prosperi
,
Elisabetta Galbiati,
Miriam Colombo,
Serena Mazzucchelli,
Agnese Salvadè,
Paolo Tortora,
Sm Doglia,
Davide Prosperi
This paper is available in a repository.
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Abstract
We present the synthesis of trastuzumab-functionalized pegylated iron oxide nanoparticles and provide an FTIR-based approach to gain a direct evidence of the actual conservation of the native structure of conjugated antibody. Their target-selectivity to specific cancer cell receptors has been also assessed.