Published in
Royal Society of Chemistry, Organic and Biomolecular Chemistry, 13(22), p. 2643-2653, 2024
DOI: 10.1039/d3ob01933k
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Application of the intramolecular Diels–Alder vinylarene (IMDAV) reaction for the synthesis of benzo-, carbocyclo-, thienothiopheneisoindolecarboxylic acids and its limitations
Journal article published in 2024 by
Elizaveta D. Yakovleva 
,
Evgeniya R. Shelukho ,
Maryana A. Nadirova,
Pavel P. Erokhin,
Daria N. Simakova,
Victor N. Khrustalev ,
Mikhail S. Grigoriev,
Anton P. Novikov ,
Anna A. Romanycheva,
Anton A. Shetnev,
Olga P. Bychkova,
Alexey S. Trenin,
Fedor I. Zubkov ,
Vladimir P. Zaytsev
,
Evgeniya R. Shelukho ,
Maryana A. Nadirova,
Pavel P. Erokhin,
Daria N. Simakova,
Victor N. Khrustalev ,
Mikhail S. Grigoriev,
Anton P. Novikov ,
Anna A. Romanycheva,
Anton A. Shetnev,
Olga P. Bychkova,
Alexey S. Trenin,
Fedor I. Zubkov ,
Vladimir P. Zaytsev
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Abstract
A concise preparative IMDAV strategy for the synthesis of benzo-, carbocyclo-, and thienothiopheneisoindolecarboxylic acids, which display antifungal and antibacterial activity, starting from readily available materials is proposed.