Published in
Royal Society of Chemistry, Chemical Communications, 10(48), p. 1475-1477, 2012
DOI: 10.1039/c1cc14713g
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Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules.
Journal article published in 2012 by
Muhammad Hanif,
Alexey A. Nazarov 
,
Anton Legin,
Michael Groessl,
Vladimir B. Arion,
Michael A. Jakupec ,
Yury O. Tsybin,
Paul J. Dyson,
Bernhard K. Keppler,
Christian G. Hartinger
,
Anton Legin,
Michael Groessl,
Vladimir B. Arion,
Michael A. Jakupec ,
Yury O. Tsybin,
Paul J. Dyson,
Bernhard K. Keppler,
Christian G. Hartinger
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Abstract
Ru(II)(arene) anticancer compounds with maleimide functionality were prepared to allow selective interaction with thiol-containing biomolecules and thereby enforcing the selective delivery of the compounds to the tumour.