Published in
Royal Society of Chemistry, Polymer Chemistry, 35(12), p. 5077-5084, 2021
DOI: 10.1039/d1py00843a
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Thermoresponsive properties of polyacrylamides in physiological solutions
Journal article published in 2021 by
Kristýna Kolouchová 
,
Volodymyr Lobaz ,
Hynek Beneš,
Victor R. de la Rosa ,
David Babuka,
Pavel Švec ,
Peter Černoch ,
Martin Hrubý ,
Richard Hoogenboom ,
Petr Štěpánek ,
Ondřej Groborz
,
Volodymyr Lobaz ,
Hynek Beneš,
Victor R. de la Rosa ,
David Babuka,
Pavel Švec ,
Peter Černoch ,
Martin Hrubý ,
Richard Hoogenboom ,
Petr Štěpánek ,
Ondřej Groborz
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Abstract
We show that the cloud point temperature (TCP) of thermoresponsive polyacrylamides is considerably lower in physiologically relevant solvents (phosphate-buffered saline, serum) than in pure water. This decrease of TCP may be critical for some biomedical applications.