Published in
Royal Society of Chemistry, Biomaterials Science, 22(9), p. 7402-7411, 2021
DOI: 10.1039/d1bm01352a
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Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22
Journal article published in 2021 by
Dana Elshaer,
M.-D. Moniruzzaman 
,
Yi Theng Ong,
Zhi Qu ,
Veronika Schreiber ,
Jakob Begun ,
Amirali Popat
,
Yi Theng Ong,
Zhi Qu ,
Veronika Schreiber ,
Jakob Begun ,
Amirali Popat
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Interleukin (IL)-22 is a multifunctional cytokine with a very short half-life that activates STAT3 and can elicit an anti-inflammatory response. We show encapsulation of IL-22 in LPMSN enhances its biological activity and stability in in vitro and human colonic organoids.