Published in
Royal Society of Chemistry, Chemical Communications, 91(57), p. 12131-12134, 2021
DOI: 10.1039/d1cc04325k
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Bidirectional modulation of microRNA with a clamp-like triplex switch for enhanced and programmed gene therapy
Journal article published in 2021 by
Lihua Zhang,
Zhen Zou 
,
Yanli Lei ,
Zhihe Qing ,
Yu Zeng,
Haiyan Sun,
Feng Feng ,
Ronghua Yang
,
Yanli Lei ,
Zhihe Qing ,
Yu Zeng,
Haiyan Sun,
Feng Feng ,
Ronghua Yang
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Abstract
In this work, a clamp-like triplex switch (CTS) was fabricated for enhanced and programmed gene therapy, which achieved bidirectional modulation of dysregulated microRNA in cancer cells in a controllable manner.