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Royal Society of Chemistry, Organic and Biomolecular Chemistry, 1(20), p. 173-181, 2022

DOI: 10.1039/d1ob02191e

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Amide-derived lysine analogues as substrates and inhibitors of histone lysine methyltransferases and acetyltransferases

Journal article published in 2022 by Jordi C. J. Hintzen ORCID, Jona Merx, Marijn N. Maas ORCID, Sabine G. H. A. Langens ORCID, Paul B. White, Thomas J. Boltje, Jasmin Mecinović ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Histone peptides containing easily accessible amide-derived lysine mimics display substrate and inhibition selectivity for biomedicinally important histone lysine methyltransferases over acetyltransferases.