Published in
Royal Society of Chemistry, Biomaterials Science, 8(10), p. 1952-1967, 2022
DOI: 10.1039/d1bm01769a
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Hyaluronic acid–amphotericin B nanocomplexes: a promising anti-leishmanial drug delivery system
Journal article published in 2022 by
R. Silva-Carvalho 
,
T. Leão ,
A. I. Bourbon ,
C. Gonçalves ,
L. M. Pastrana,
P. Parpot ,
I. Amorim,
A. M. Tomás,
F. M. Gama
,
T. Leão ,
A. I. Bourbon ,
C. Gonçalves ,
L. M. Pastrana,
P. Parpot ,
I. Amorim,
A. M. Tomás,
F. M. Gama
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Abstract
Hyaluronic acid-Amphotericin B self-assembled nanocomplexes obtained by a simple drug-polysaccharide non-covalent association in an amorphous state exhibit potent anti-leishmanial activity and can overcome drug toxicity.