Published in
Royal Society of Chemistry, Green Chemistry, 12(24), p. 4859-4869, 2022
DOI: 10.1039/d2gc00724j
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Mechanochemical Fischer indolisation: an eco-friendly design for a timeless reaction
Journal article published in 2022 by
Andrea Porcheddu 
,
Rita Mocci ,
Margherita Brindisi ,
Federico Cuccu ,
Claudia Fattuoni ,
Francesco Delogu ,
Evelina Colacino ,
Maria Valeria D'Auria
,
Rita Mocci ,
Margherita Brindisi ,
Federico Cuccu ,
Claudia Fattuoni ,
Francesco Delogu ,
Evelina Colacino ,
Maria Valeria D'Auria
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Abstract
We developed an environmentally friendly mechanochemical protocol to induce an effective Fischer indolisation to synthesize indoles and indolines taking advantage of oxalic acid and dimethylurea.