Published in
Royal Society of Chemistry, Biomaterials Science, 14(10), p. 3770-3792, 2022
DOI: 10.1039/d2bm00729k
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In vitro study of polydopamine nanoparticles as protective antioxidant agents in fibroblasts derived from ARSACS patients
Journal article published in 2022 by
Matteo Battaglini 
,
Alessio Carmignani,
Chiara Martinelli,
Jamila Colica,
Attilio Marino ,
Stefano Doccini ,
Valentina Mollo,
Francesca Santoro ,
Martina Bartolucci,
Andrea Petretto,
Filippo Maria Santorelli,
Gianni Ciofani
,
Alessio Carmignani,
Chiara Martinelli,
Jamila Colica,
Attilio Marino ,
Stefano Doccini ,
Valentina Mollo,
Francesca Santoro ,
Martina Bartolucci,
Andrea Petretto,
Filippo Maria Santorelli,
Gianni Ciofani
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Abstract
PDNPs elicit an antioxidant effect on healthy and ARSACS-derived fibroblasts, thus reducing ROS levels, ROS-induced apoptosis/necrosis, and ROS-induced mitochondrial impairments, and enhancing protein expression.