Published in
Royal Society of Chemistry, Organic and Biomolecular Chemistry, 38(21), p. 7813-7820, 2023
DOI: 10.1039/d3ob01261a
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The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe
Journal article published in 2023 by
Chi-Lin Kuo,
Qin Su,
Adrianus M. C. H. van den Nieuwendijk,
Thomas J. M. Beenakker 
,
Wendy A. Offen,
Lianne I. Willems ,
Rolf G. Boot,
Alexi J. Sarris,
André R. A. Marques ,
Jeroen D. C. Codée ,
Gijsbert A. van der Marel,
Bogdan I. Florea ,
Gideon J. Davies ,
Herman S. Overkleeft ,
Johannes M. F. G. Aerts
,
Wendy A. Offen,
Lianne I. Willems ,
Rolf G. Boot,
Alexi J. Sarris,
André R. A. Marques ,
Jeroen D. C. Codée ,
Gijsbert A. van der Marel,
Bogdan I. Florea ,
Gideon J. Davies ,
Herman S. Overkleeft ,
Johannes M. F. G. Aerts
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Abstract
Acid β-galactosidase (GLB1) and galactocerebrosidase (GALC) are retaining exo-β-galactosidases involved in lysosomal glycoconjugate metabolism.