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Royal Society of Chemistry, Chemical Communications, 56(58), p. 7769-7772, 2022

DOI: 10.1039/d2cc02874c

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Selective recognition of A/T-rich DNA 3-way junctions with a three-fold symmetric tripeptide

Journal article published in 2022 by Jacobo Gómez-González, Laura Martínez-Castro ORCID, Juan Tolosa-Barrilero ORCID, Ana Alcalde-Ordóñez ORCID, Soraya Learte-Aymamí ORCID, Miguel Vázquez López ORCID, José L. Mascareñas ORCID, M. Eugenio Vázquez ORCID, Joaquín C. García-Martínez ORCID, José Martínez-Costas ORCID, Jean-Didier Maréchal ORCID, Miguel Vázquez López, M. Eugenio Vázquez
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We describe a new approach to target non-canonical DNA 3-Way Junctions (3WJs) that relies on the cooperative and sequence-selective recognition of A/T-rich duplex DNA branches by three AT-Hook peptides attached to a three-fold symmetric and fluorogenic 1,3,5-tristyrylbenzene core.