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Royal Society of Chemistry, Chemical Communications, 42(58), p. 6188-6191, 2022
DOI: 10.1039/d2cc01144a
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A conformational study of the 10–23 DNAzyme via programmed DNA self-assembly
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Abstract
We have developed a strategy to study the interhelical angle of two DNA duplexes in nucleic acids as exemplified by the 10–23 DNAzyme. The nucleic acids are programmed to assemble into large 2D arrays to reduce random conformation fluctuation and facilitate the conformation study.