Dissemin is shutting down on January 1st, 2025

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Royal Society of Chemistry, Biomaterials Science, 6(11), p. 2103-2114, 2023

DOI: 10.1039/d2bm01835g

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Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

Full text: Unavailable

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Data provided by SHERPA/RoMEO

Abstract

Polymeric nanoparticles containing Bedaquiline reduce bacterial burden and improve survival in Mycobacterium marinum infected zebrafish. The nanoparticles accumulate in tuberculosis granulomas and in endothelial cells ending up in late endosomes.