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Royal Society of Chemistry, CrystEngComm, 37(23), p. 6495-6505, 2021

DOI: 10.1039/d1ce00387a

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Tunable protein crystal size distribution via continuous slug-flow crystallization with spatially varying temperature

Journal article published in 2021 by Nicholas J. Mozdzierz, Moo Sun Hong ORCID, Yongkyu Lee, Moritz H. P. Benisch, Mo Jiang ORCID, Allan S. Myerson ORCID, Richard D. Braatz ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Under appropriate buffer and pH conditions, the magnitude and dispersion of the product protein crystals were reproducibly manipulated by controlling the spatial temperature along the tube in a continuous tubular crystallizer.