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Royal Society of Chemistry, Organic and Biomolecular Chemistry, 17(19), p. 3763-3775, 2021

DOI: 10.1039/d1ob00143d

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Enantioselective construction of the 8-azabicyclo[3.2.1]octane scaffold: application in the synthesis of tropane alkaloids

Journal article published in 2021 by Sandra Rodriguez, Uxue Uria ORCID, Efraim Reyes ORCID, Liher Prieto ORCID, Marta Rodríguez-Rodríguez, Luisa Carrillo ORCID, Jose L. Vicario ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The 8-azabicyclo[3.2.1]octane core is the central motif of tropane alkaloids. This review compiles the methodologies employed to synthesize this scaffold in an enantioenriched form from achiral starting materials.