Published in
Royal Society of Chemistry, Nanoscale, 12(13), p. 6212-6226, 2021
DOI: 10.1039/d0nr06464e
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Stiffening of DU145 prostate cancer cells driven by actin filaments – microtubule crosstalk conferring resistance to microtubule-targeting drugs
Journal article published in 2021 by
Andrzej Kubiak 
,
Matteo Chighizola ,
Carsten Schulte ,
Natalia Bryniarska ,
Julita Wesołowska ,
Maciej Pudełek,
Małgorzata Lasota,
Damian Ryszawy ,
Agnieszka Basta-Kaim ,
Piotr Laidler,
Alessandro Podestà ,
Małgorzata Lekka
,
Matteo Chighizola ,
Carsten Schulte ,
Natalia Bryniarska ,
Julita Wesołowska ,
Maciej Pudełek,
Małgorzata Lasota,
Damian Ryszawy ,
Agnieszka Basta-Kaim ,
Piotr Laidler,
Alessandro Podestà ,
Małgorzata Lekka
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Abstract
Cell stiffening induced by anticancer microtubule targeting drugs (MTDs) such as vinflunine (VFL), colchicine (COL), and docetaxel (DTX) can be driven by crosstalk between actin filaments and microtubules.