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Royal Society of Chemistry, Chemical Communications, 90(59), p. 13490-13493, 2023

DOI: 10.1039/d3cc04448c

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Supramolecular intermediates in thermo-mechanochemical direct amidations

This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We present a solvent-free thermo-mechanochemical approach for the direct coupling of carboxylic acids and amines, which avoids activators and additives. Non-covalent interactions between the reagents guide the formation of the amide bond.