Published in
Royal Society of Chemistry, Organic and Biomolecular Chemistry, 48(19), p. 10575-10586, 2021
DOI: 10.1039/d1ob01825f
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Structure–antitumor activity relationships of tripodal imidazolium-amino acid based salts. Effect of the nature of the amino acid, amide substitution and anion
Journal article published in 2021 by
Adriana Valls 
,
Belén Altava ,
Vladimir Aseyev,
Israel Carreira-Barral ,
Laura Conesa,
Eva Falomir,
Eduardo García-Verdugo ,
Santiago Vicente Luis ,
Roberto Quesada
,
Belén Altava ,
Vladimir Aseyev,
Israel Carreira-Barral ,
Laura Conesa,
Eva Falomir,
Eduardo García-Verdugo ,
Santiago Vicente Luis ,
Roberto Quesada
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Abstract
Imidazolium tripodal compounds derived from amino acids presented good cancer cell growth inhibition against different cancer cell lines, increasing the inhibition when in vitro experiments were carried out at acidic pHe.