Published in
Royal Society of Chemistry, New Journal of Chemistry, 31(46), p. 14967-14978, 2022
DOI: 10.1039/d2nj01980a
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Design, synthesis, anticancer activity and molecular docking studies of new benzimidazole derivatives bearing 1,3,4-oxadiazole moieties as potential thymidylate synthase inhibitors
Journal article published in 2022 by
Abdulraheem Sa Almalki,
Syed Nazreen 
,
Serag Eldin I. Elbehairi,
Mohammad Asad,
Ali A. Shati,
Mohammad Y. Alfaifi,
Abdulrahman Alhadhrami ,
Ahmed A. Elhenawy ,
Ali Q. Alorabi,
Abdullah M. Asiri ,
Mohammad Mahboob Alam
,
Serag Eldin I. Elbehairi,
Mohammad Asad,
Ali A. Shati,
Mohammad Y. Alfaifi,
Abdulrahman Alhadhrami ,
Ahmed A. Elhenawy ,
Ali Q. Alorabi,
Abdullah M. Asiri ,
Mohammad Mahboob Alam
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Abstract
Compounds 10 and 14 arrest the cell cycle at the G1 phase and induce apoptosis without any necrosis in MDA-MB-231 cells.