Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
Journal article published in 2021 by
George E. Stenhouse 
,
Khuzwayo C. Jere ,
Chikondi Peno,
Rebecca J. Bengtsson,
End Chinyama,
Jonathan Mandolo,
Amy K. Cain ,
Miren Iturriza-Gómara,
Naor Bar-Zeev ,
Nigel A. Cunliffe ,
Jennifer Cornick,
Kate S. Baker
,
Khuzwayo C. Jere ,
Chikondi Peno,
Rebecca J. Bengtsson,
End Chinyama,
Jonathan Mandolo,
Amy K. Cain ,
Miren Iturriza-Gómara,
Naor Bar-Zeev ,
Nigel A. Cunliffe ,
Jennifer Cornick,
Kate S. Baker
This paper is made freely available by the publisher.
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Abstract
Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.