Published in
Royal Society of Chemistry, Organic and Biomolecular Chemistry, 2(21), p. 345-350, 2023
DOI: 10.1039/d2ob01763f
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A Cu-BOX catalysed enantioselective Mukaiyama-aldol reaction with difluorinated silyl enol ethers and acylpyridine N-oxides
Journal article published in 2023 by
Amparo Sanz-Marco 
,
Daniel Esperilla,
Marc Montesinos-Magraner ,
Carlos Vila ,
M. Carmen Muñoz ,
José R. Pedro ,
Gonzalo Blay
,
Daniel Esperilla,
Marc Montesinos-Magraner ,
Carlos Vila ,
M. Carmen Muñoz ,
José R. Pedro ,
Gonzalo Blay
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Abstract
Chiral difluorinated tertiary alcohols are obtained in moderate to excellent yields and high enantioselectivities upon a Cu(ii)-catalysed reaction of difluorinated silyl enol ethers and acylpyridine N-oxides.