Published in
Royal Society of Chemistry, Lab on a Chip, 20(21), p. 3876-3887, 2021
DOI: 10.1039/d1lc00685a
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A multiplexed ion-exchange membrane-based miRNA (MIX·miR) detection platform for rapid diagnosis of myocardial infarction
Journal article published in 2021 by
Xiang Ren 
,
Bradley W. Ellis,
George Ronan,
Stuart Ryan Blood,
Cameron DeShetler,
Satyajyoti Senapati,
Keith L. March,
Eileen Handberg,
David Anderson,
Carl Pepine ,
Hsueh-Chia Chang ,
Pinar Zorlutuna
,
Bradley W. Ellis,
George Ronan,
Stuart Ryan Blood,
Cameron DeShetler,
Satyajyoti Senapati,
Keith L. March,
Eileen Handberg,
David Anderson,
Carl Pepine ,
Hsueh-Chia Chang ,
Pinar Zorlutuna
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Abstract
This work reports a multiplexed ion-exchange membrane-based miRNA sensor, namely MIX·miR, for detection of multiple specific cardiac-associated exosomal miRNA markers in clinical plasma samples with concentrations as low as 1 pM.