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Royal Society of Chemistry, Chemical Society Reviews, 14(51), p. 6210-6221, 2022

DOI: 10.1039/d2cs00339b

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The importance of cellular degradation kinetics for understanding mechanisms in targeted protein degradation

Journal article published in 2022 by Kristin M. Riching ORCID, Elizabeth A. Caine ORCID, Marjeta Urh ORCID, Danette L. Daniels ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Targeted protein degradation is a dynamic process regulated not only by the kinetics and mechanisms of the degrader compound, but also the native homeostasis and cellular regulation of the target protein. Image created with BioRender.com.