Published in
Royal Society of Chemistry, Green Chemistry, 16(24), p. 6156-6167, 2022
DOI: 10.1039/d1gc04714k
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Light-driven hydroxylation of testosterone by Synechocystis sp. PCC 6803 expressing the heterologous CYP450 monooxygenase CYP110D1
Journal article published in 2022 by
Francesco Mascia,
Sara B. Pereira,
Catarina C. Pacheco 
,
Paulo Oliveira ,
Jennifer Solarczek,
Anett Schallmey ,
Robert Kourist ,
Véronique Alphand ,
Paula Tamagnini
,
Paulo Oliveira ,
Jennifer Solarczek,
Anett Schallmey ,
Robert Kourist ,
Véronique Alphand ,
Paula Tamagnini
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Abstract
Biotransformation of testosterone into 15β-hydroxytestosterone by the cyanobacterium Synechocystis expressing the heterologous monooxygenase CYP110D1. The reaction is sustained by reducing equivalents and oxygen provided by oxygenic photosynthesis.