Published in
Royal Society of Chemistry, Nanoscale, 36(14), p. 13261-13273, 2022
DOI: 10.1039/d2nr01818g
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Polymer-tethered glycosylated gold nanoparticles recruit sialylated glycoproteins into their protein corona, leading to off-target lectin binding
Journal article published in 2022 by
Ashfaq Ahmad 
,
Panagiotis G. Georgiou ,
Alessia Pancaro ,
Muhammad Hasan ,
Inge Nelissen,
Matthew I. Gibson
,
Panagiotis G. Georgiou ,
Alessia Pancaro ,
Muhammad Hasan ,
Inge Nelissen,
Matthew I. Gibson
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Abstract
Upon exposure to biological fluids, the fouling of nanomaterial surfaces results in non-specific capture of proteins, which is particularly important when in contact with blood serum for in vivo and ex vivo applications.