Published in
Royal Society of Chemistry, Lab on a Chip, 20(21), p. 3963-3978, 2021
DOI: 10.1039/d1lc00494h
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Peristaltic on-chip pump for tunable media circulation and whole blood perfusion in PDMS-free organ-on-chip and Organ-Disc systems
Journal article published in 2021 by
Stefan Schneider 
,
Marvin Bubeck ,
Julia Rogal ,
Huub J. Weener ,
Cristhian Rojas,
Martin Weiss,
Michael Heymann ,
Andries D. van der Meer ,
Peter Loskill
,
Marvin Bubeck ,
Julia Rogal ,
Huub J. Weener ,
Cristhian Rojas,
Martin Weiss,
Michael Heymann ,
Andries D. van der Meer ,
Peter Loskill
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Abstract
We present an Organ-Disc with integrated peristaltic pump for the closed-loop perfusion of microphysiological systems with tunable flow rates, enabling time-resolved monitoring of cell states and media properties, and the perfusion of whole blood.