Published in
Royal Society of Chemistry, Biomaterials Science, 5(11), p. 1704-1713, 2023
DOI: 10.1039/d2bm01836e
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Transdermal delivery of allopurinol to acute hyperuricemic mice via polymer microneedles for the regulation of serum uric acid levels
Journal article published in 2023 by
Rui Wang,
Han Wang,
Guohua Jiang 
,
Yanfang Sun,
Tianqi Liu,
Lei Nie,
Amin Shavandi ,
Khaydar E. Yunusov,
Uladzislau E. Aharodnikau ,
Sergey O. Solomevich
,
Yanfang Sun,
Tianqi Liu,
Lei Nie,
Amin Shavandi ,
Khaydar E. Yunusov,
Uladzislau E. Aharodnikau ,
Sergey O. Solomevich
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Abstract
Polymer microneedle patches for transdermal delivery of anti-hyperuricemia drugs (Allopurinol, AP) have been developed for regulating serum uric acid levels, reducing adverse reactions and improving the bioavailability of AP.