Royal Society of Chemistry, Organic and Biomolecular Chemistry, 5(21), p. 1000-1007, 2023
DOI: 10.1039/d2ob01911f
Full text: Unavailable
Trisubstituted TPA/TPB-based ligands containing linear and macrocyclic polyamines show strong G-quadruplex stabilisation and selectivity over duplex DNA. Encapsulation in AS1411 aptamer-targeted liposomes dramatically increases their cytotoxicity.