Published in
Royal Society of Chemistry, Nanoscale, 17(13), p. 8012-8016, 2021
DOI: 10.1039/d1nr01094h
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Single molecular nanomedicine with NIR light-initiated superoxide radical, singlet oxygen and thermal generation for hypoxia-overcoming cancer therapy
Journal article published in 2021 by
Jipsa Chelora,
Yuchao Liang,
Wei-Chih Wei,
Xiao Cui 
,
Yafang Xiao ,
Yingpeng Wan ,
Zhongming Huang ,
Shuang Tian,
Shengliang Li ,
Yi-Hsuan Huang,
Ken-Tsung Wong ,
Chun-Sing Lee
,
Yafang Xiao ,
Yingpeng Wan ,
Zhongming Huang ,
Shuang Tian,
Shengliang Li ,
Yi-Hsuan Huang,
Ken-Tsung Wong ,
Chun-Sing Lee
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Abstract
Molecular nanomedicine (BthB NPs) is developed for effective superoxide radical (O2˙−) generation for hypoxia-overcoming photodynamic therapy (PDT), upon irradiation with an 808 nm laser with a high tissue penetration depth.