Published in
Royal Society of Chemistry, Chemical Communications, 28(57), p. 3457-3460, 2021
DOI: 10.1039/d1cc00957e
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A dual-enzyme cleavable linker for antibody–drug conjugates
Journal article published in 2021 by
Jonathan D. Bargh 
,
Stephen J. Walsh ,
Nicola Ashman ,
Albert Isidro-Llobet ,
Jason S. Carroll ,
David R. Spring
,
Stephen J. Walsh ,
Nicola Ashman ,
Albert Isidro-Llobet ,
Jason S. Carroll ,
David R. Spring
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
A 3-O-sulfo-β-galactose linker is cleaved by two lysosomal enzymes to release payloads from ADCs at targeted cancer cells.