Published in
Royal Society of Chemistry, Lab on a Chip, 2(22), p. 326-342, 2022
DOI: 10.1039/d1lc00669j
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Intestinal explant barrier chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants
Journal article published in 2022 by
Hossein Eslami Amirabadi 
,
Joanne M. Donkers ,
Esmée Wierenga,
Bastiaan Ingenhut,
Lisanne Pieters,
Lianne Stevens,
Tim Donkers,
Joost Westerhout,
Rosalinde Masereeuw ,
Ivana Bobeldijk-Pastorova,
Irene Nooijen,
Evita van de Steeg
,
Joanne M. Donkers ,
Esmée Wierenga,
Bastiaan Ingenhut,
Lisanne Pieters,
Lianne Stevens,
Tim Donkers,
Joost Westerhout,
Rosalinde Masereeuw ,
Ivana Bobeldijk-Pastorova,
Irene Nooijen,
Evita van de Steeg
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Abstract
The Intestinal Explant Barrier Chip (IEBC) mechanically fixes human and porcine intestinal tissue explants between an apical and basolateral microchannel and is the first microphysiological system to study intestinal drug absorptionex vivo.