Published in
Royal Society of Chemistry, Dalton Transactions, 18(50), p. 6071-6075, 2021
DOI: 10.1039/d1dt00740h
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An unexpected in-solution instability of diiodido analogue of picoplatin complicates its biological characterization
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Abstract
Complex cis-[PtI2(NH3)(pic)] (pic = 2-methylpyridine), an iodido analogue of picoplatin, released the N-donor pic ligand in solution and isomerized, which complicates its subsequent testing for cytotoxicity.