In vivo active organometallic-containing antimycotic agents
Journal article published in 2021 by
Riccardo Rubbiani,
Tobias Weil 
,
Noemi Tocci ,
Luciano Mastrobuoni,
Severin Jeger,
Marco Moretto ,
James Ng ,
Yan Lin ,
Jeannine Hess ,
Stefano Ferrari ,
Andres Kaech,
Luke Young ,
John Spencer ,
Anthony L. Moore ,
Kevin Cariou
and other authors.
,
Noemi Tocci ,
Luciano Mastrobuoni,
Severin Jeger,
Marco Moretto ,
James Ng ,
Yan Lin ,
Jeannine Hess ,
Stefano Ferrari ,
Andres Kaech,
Luke Young ,
John Spencer ,
Anthony L. Moore ,
Kevin Cariou
and other authors.
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Abstract
Fungal infections represent a global problem and there is an urgent need for new drugs. In this work, we prepared four novel organometallic derivatives of the frontline antifungal drug fluconazole with very promising in vivo activity.