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RSC Medicinal Chemistry, 12(12), p. 2065-2070, 2021

DOI: 10.1039/d1md00245g

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2-Difluoromethylpyridine as a bioisosteric replacement of pyridine-N-oxide: the case of quorum sensing inhibitors

Journal article published in 2021 by Truong Thanh Tung ORCID, Thang Nguyen Quoc
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Herein, we demonstrate that 2-difluoromethylpyridine is a bioisosteric replacement of pyridine-N-oxide. This work could open a new path for bioisosteric replacement in drug discovery and development.