Published in
Royal Society of Chemistry, Nanoscale, 40(13), p. 16909-16922, 2021
DOI: 10.1039/d1nr03553c
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Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma
Journal article published in 2021 by
Taskeen Iqbal Janjua 
,
Aria Ahmed-Cox ,
Anand Kumar Meka,
Friederike M. Mansfeld,
Helen Forgham,
Rosa Mistica C. Ignacio,
Yuxue Cao,
Joshua A. McCarroll,
Roberta Mazzieri ,
Maria Kavallaris ,
Amirali Popat
,
Aria Ahmed-Cox ,
Anand Kumar Meka,
Friederike M. Mansfeld,
Helen Forgham,
Rosa Mistica C. Ignacio,
Yuxue Cao,
Joshua A. McCarroll,
Roberta Mazzieri ,
Maria Kavallaris ,
Amirali Popat
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Abstract
In this work, we successfully synthesise novel ultra-small (30 nm), large pore (7 nm) silica nanoparticles conjugated with lactoferrin a targeting ligand and demonstrate its utility for improving drug delivery across brain to treat Glioblastoma.