Published in
Royal Society of Chemistry, Journal of Materials Chemistry B: Materials for biology and medicine, 42(9), p. 8823-8831, 2021
DOI: 10.1039/d1tb01315g
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Barnase encapsulation into submicron porous CaCO3 particles: studies of loading and enzyme activity
Journal article published in 2021 by
Alexey M. Yashchenok 
,
Olga I. Gusliakova ,
Elena V. Konovalova ,
Marina V. Novoselova ,
Victoria O. Shipunova ,
Tatiana O. Abakumova ,
Olga I. Efimova ,
Roman Kholodenko ,
Alexey A. Schulga ,
Timofei S. Zatsepin,
Dmitry A. Gorin ,
Sergey M. Deyev
,
Olga I. Gusliakova ,
Elena V. Konovalova ,
Marina V. Novoselova ,
Victoria O. Shipunova ,
Tatiana O. Abakumova ,
Olga I. Efimova ,
Roman Kholodenko ,
Alexey A. Schulga ,
Timofei S. Zatsepin,
Dmitry A. Gorin ,
Sergey M. Deyev
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Abstract
The encapsulation efficiency of ribonuclease barnase in submicron CaCO3 particles can be enhanced by the use of anionic polyelectrolytes. The enzymatic activity of enzyme loaded particles is consistent with the loading capacity of these particles.