Published in
Royal Society of Chemistry, Analyst, 19(146), p. 6014-6025, 2021
DOI: 10.1039/d1an01078f
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Micro-Raman spectroscopy of lipid halo and dense-core amyloid plaques: aging process characterization in the Alzheimer's disease APPswePS1ΔE9 mouse model
Journal article published in 2021 by
Emerson A. Fonseca 
,
Lucas Lafeta ,
João Luiz Campos ,
Renan Cunha ,
Alexandre Barbosa ,
Marco A. Romano-Silva ,
Rafael Vieira ,
Leandro M. Malard ,
Ado Jorio
,
Lucas Lafeta ,
João Luiz Campos ,
Renan Cunha ,
Alexandre Barbosa ,
Marco A. Romano-Silva ,
Rafael Vieira ,
Leandro M. Malard ,
Ado Jorio
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Abstract
Hyperspectral Raman imaging of amyloid plaques and lipid halo in the brains of mice were able to differentiate control, young and aged Alzheimer's disease transgenic mouse models.